Primo & E2

[swolleymolley9090]

So my e2 gets up to 237 pg/mL on 500mg test would it be safe to say a 1:1 ratio of test/primo wouldn’t tank estrodial or possibly even primo slightly higher? I know it’s mostly person dependent but was curious how others have ran primo with e2 around that range.

 

[CaptainAmerica]

I don’t think that primo is even enough to get that e2 to a proper place. You’re gonna need an ai IMO

 

[swolleymolley9090]

@CaptainAmerica I’ve ran 700mg/wk the last 6 weeks of first blast and never had any high e2 sides, I’ve heard a lot say don’t take an a.I unless you get sides but then some say e2 can be elevated but not too much whether you’re experiencing sides or not. Would you say e2 that high is too much even without sides?

 

[CaptainAmerica]

@swolleymolley9090 I would say so yes. E2 is anabolic to a certain degree. I like to keep mine about 60 which is a tad above reference ranges.

 

[Gettingolder]

swolleymolley9090 said:

@captainamerica I’ve ran 700mg/wk the last 6 weeks of first blast and never had any high e2 sides, I’ve heard a lot say don’t take an a.I unless you get sides but then some say e2 can be elevated but not too much whether you’re experiencing sides or not. Would you say e2 that high is too much even without sides?

Look up Deep Vein Thrombosis and pericardial effusion.

Am I saying you will develop those no not at all but you should always have all the information you can about what may happen over time.

" But But bro estrogen is anabolic and you will limit yer Gainz bro"

Yeah estro is important for cardio health and brain health and a proper functioning immune system and innumerous other functions in the male body.
Just because you do not experience outright side effects does not mean you are possibly not having long term changes and or issues down the road.

Like one adrol 50 a day for 4 weeks is not usually a big deal but make that one a day for a couple years and its fully different.

Your doing blood work which is really good considering so many do not. You are already ahead of most in being able to make decisions that are best for you and your health.

 

[Leggies]

Agree with Cap. I don’t think primo would be enough to crash e2. But I would use an AI that e2 is pretty high.

 

[swolleymolley9090]

@Gettingolder yea trying to be on the safer side of things,hence the reason I chose primo as a possible second compound. I’ll most likely try to get primo a bit higher than test if I can, would rather just run more primo since I’ll have it than to run an a.I on top, thinking 350 test/primo and if bloods allow it drop to 250 test with 400 primo. Just trying to run I mild summer blast mostly for aesthetics, potential recomp, while also getting comfortable with a second compound before blasting with it in a bulk later in the year

 

[swolleymolley9090]

@Leggies @CaptainAmerica I’d prefer to just run a higher primo to test ratio instead of an a.I on top unless I have to, I’ll pretty much just go off of how bloods look and try to keep e2 closer to the reference range

 

[CaptainAmerica]

@swolleymolley9090 except that you won’t see any effect of primo for 5 weeks minimum and primo is expensive.

Do what you will of course but it’s not the route I’d take for e2 control

 

[MikeAlstott]

No one here can tell you for sure. Primo seems to act as an estrogen controller as it competes for aromatase basically preventing testosterone from aromatizing into estrodial. You will need to try it out for yourself and see if you start experiencing any high estrogen side effects and if you do then you can start an AI. A 1:1 ratio of Test to Primo is a great place to start and then you can adjust it from there.

I’d honestly start as low as 200/200 for 4 weeks and then up the dose every 4 weeks.

 

[swolleymolley9090]

I’ll probably just add primo to my cruise dose and titrate up from there, If I can’t get e2 in range I’ll add an a.i. plan on keeping e2 in the reference range or slightly over while blasting but I’ve never been told the impacts of high e2 long term even without sides until now, just how it’s neuro and cardioprotective but then again too much of anything can be bad and I’ll definitely have to take that into consideration

 

[MikeAlstott]

@swolleymolley9090 you’re going to have to throw the “in range” shit out when your dealing with Test levels above reference range. It’s more about having a good ratio between the hormone levels and being aware of sides. Beginning with a cruise dose and matching that is a smart place to start and is the more conservative approach. You will want to monitor sides. If you don’t get any side effects and your hormones are done leveling out after a few weeks than you should be good. I’d be surprised if you needed an AI at these dosages to start, but everyone is different.

@CaptainAmerica I don’t think that’s necessarily true in regards to Primo’s estrogen controlling effects. I’m assuming you’re referring to Primo E reaching full saturation after around the five week mark. I’d agree with you then that the noticeable anabolic effects from it most commonly occur around that point. But the other effects, like estrogen control, are going to onset much faster than that, if not immediately and coincide with the change in Test dosage.

 

[swolleymolley9090]

@MikeAIstott my e2 just gets really high with 500mg/wk but I never get sides (237 pg/mL) I’m cruising on 200mg (puts my trough at 1040 ng/dL) I plan on getting bloodwork and see where estrogen is at cruise dose and go from there.

 

[smalldelts]

200/200 primo/test puts my e2 in the mid to low 20s. Normally would be 40-50

 

[swolleymolley9090]

@smalldelts thats good to know, my e2 is 97 on cruise right now so I’m trying to see if 200/200 will bring it down to around 40-50 but if it’s a bit higher than that I’m gonna try 200-300 to see where that puts me, I got dbol on hand just in case