Nasal administration of testosterone…

[EnhancedPrimate]

Wondering if anyone has ever tried taking testosterone or any AAS up the nose?

Snorting straight powder, nasal spray, or stuffed a piece of gauze in a nostril that was dabbed in a oil solution with the hormone?

 

[psauce]

There’s a company that’s been developing a nasal gel for a while. It has to be pretty far into the trial process now. There’s also an oral version, a little pod you adhere to your gum that absorbs through your cheek. Never tried either, not super interested, but it’s evidently a way to do it. I’m not sure if you’d use an oil if you tried it DIY, though.

 

[EnhancedPrimate]

There’s a company that’s been developing a nasal gel for a while. It has to be pretty far into the trial process now. There’s also an oral version, a little pod you adhere to your gum that absorbs through your cheek. Never tried either, not super interested, but it’s evidently a way to do it. I’m not sure if you’d use an oil if you tried it DIY, though.

Only tried it by snorting raw powder, it’s effective, but it’s different. I noticed it was far more nootropic then physical in effects.

I’m not familiar with the gel you’re referring too, and had no idea there’s already trials being done on a nasal administered testosterone. So that’s interesting to discover I’ll be looking into it more.

I’m assuming the gel is just lubricating the nostril to absorb through the nasal membrane which is the same as the oil. The reason I detailed the oil is because testosterone isn’t water soluble so I would imagine it wouldn’t be able to constituted into a nasal mist spray.

I like the idea of it, would be a nice addition to any protocol. Much different then sublingual because of the nootropic effects I noticed snorting some powder.

Do you know the name of the company?

 

[psauce]

The product is called Natesto, it’s out on the market. Here’s a paper that introduces it. Here’s a recent paper about how men with varying baseline T levels respond.

You take it three times a day. If you look at the first figure in the second link, you see why… big peak, but effectively back to baseline in six hours. Sort of the downside of using non-esterified test.

They’ve got a full product website and everything, plenty of info out there. If you wanted to try to mimic their gel preparation, the ingredients are listed on page 3 of their medication guide, here. Looks pretty simple, honestly.

 

[jumdumpster]

The product is called Natesto, it’s out on the market. Here’s a paper that introduces it. Here’s a recent paper about how men with varying baseline T levels respond.

You take it three times a day. If you look at the first figure in the second link, you see why… big peak, but effectively back to baseline in six hours. Sort of the downside of using non-esterified test.

They’ve got a full product website and everything, plenty of info out there. If you wanted to try to mimic their gel preparation, the ingredients are listed on page 3 of their medication guide, here. Looks pretty simple, honestly.

wow that’s actually really cool
Its like tne but you snort it
id go insane on that

 

[BPrime2]

wow that’s actually really cool
Its like tne but you snort it
id go insane on that

ok so, we need a madman to make a PWO spray with tne/trne/halo/cheque drops/mtren - Murder Mist

 

[jumdumpster]

ok so, we need a madman to make a PWO spray with tne/trne/halo/cheque drops/mtren - Murder Mist

halo/test mist would be unreal

 

[Tug]

They make Natesto with colloidal silicon dioxide. Allows it to disperse evenly in the spray. But silicon dioxide is silica which is sand, except it is nano particle sized, meaning it can enter cells and cause problems. I’d rather do a lozenge. Or ideally just a spray without nano-glass in it.

 

[psauce]

That's nonsense. You don't know the size of the silica. It's been approved by FDA and there's information on adverse affects. You're talking out of your ass without any proof on one front and making claims that you could substantiate but don't on the other.

 

[Tug]

That's nonsense. You don't know the size of the silica. It's been approved by FDA and there's information on adverse affects. You're talking out of your ass without any proof on one front and making claims that you could substantiate but don't on the other.

Re-evaluation of silicon dioxide as a food additive

“The food additive, silicon dioxide (E 551), is a material comprised of aggregated nanosized primary particles. These aggregates can further agglomerate to form larger structures. The sizes of the aggregates and agglomerates are normally greater than 100 nm. However, depending on the starting material and/or on the manufacturing process, it cannot be totally excluded that some aggregates of primary particles could be smaller than 100 nm in size.”

I am not in the business of trusting the FDA or any of the captured/crooked regulatory institutions to tell me what is safe. The European agency doesn’t consider it safe. Further:
Oral intake of silica nanoparticles exacerbates intestinal inflammation

Its powdered glass, even in small amounts I’m not keen to insufflate it.